Dɪɢɪᴛᴀʟɪs Pᴜʀᴘᴜʀᴇᴀ @encelado@mastodon.sdf.org

Solvay Prize in Chemistry goes to mRNA pioneer Katalin Karikó, for development of COVID-19 vaccines. #mrna #vaccines #medicine #womeninscience https://www.nature.com/articles/d42473-022-00016-1

Researchers use CRISPR-Cas9 gene-editing sysyem to build cell models of melanoma, the deadliest skin cancer. #medicine #genomics #cancer #crisprcas9

https://www.broadinstitute.org/news/researchers-use-crispr-build-melanoma-models-scratch-using-human-cells

More than 1 million children in Ghana, Kenya and Malawi have now received one or more doses of the world’s first #malaria vaccine, thanks to a pilot program coordinated by WHO. #health #medicine #infectivology #vaccine
https://www.who.int/news/item/21-04-2022-over-1-million-african-children-protected-by-first-malaria-vaccine

Tuberculosis and COVID-19 are the leading infectious causes of death globally.
On WorldTBDay, a new Lancet Respiratory Medicine-eBioMedicine Series examines these intersecting pandemics and the wide-ranging efforts needed to tackle them.
#medicine #health #infectivology
https://hubs.li/Q016G_Hf0

Notes on Doctoring: Dr. Stanley and the covenant of Medicine

Medicine is a profession, he says, more like a covenant than a contract. “Doctoring,” Stanley calls it: “You get the privilege of meeting people in some of the most beautiful or strange or horrible parts of their lives.” And it’s important to remember, “Every patient is an N of 1,” he says, borrowing the term for a clinical trial in which a single patient is the only subject. #medicine #healthcare #humanism
https://www.harvardmagazine.com/2022/01/alumni-michael-stanley

Dr. Kelly Ann Fearnley lives with long COVID and persistent neurological and neurocognitive symptoms. In this article, she talks about her experiences #medicine #covid19 #neurology #psychiatry https://www.medicalnewstoday.com/articles/through-my-eyes-long-neuro-covid

The Healing Power of Patient Stories

“A new diagnosis is just the starting point. The patient will then begin their journey of integrating this diagnosis into their life, into their relationships and their identity. In this webinar, Annie Brewster, MD, will discuss the power of patient stories and how they can improve health care and spur innovations that meet patient needs.„
#medicine #healthcare
https://executiveeducation.hms.harvard.edu/thought-leadership/webinar-series/healing-power-patient-stories

A friend just returned this to me. Had totally forgotten about me lending it to her. The Motorcycle Diaries – Che Guevara, is definitely one of my favourite books and one of those which influenced my life most.
#books #memoir #journey #cheguevera #marxism #socialinjustice #medicine

NEJM hard copy
#medicine #neurology #peerreviewed #journal

Study reveals  fine particle pollution may contribute to racial/ethnic disparities in the prevalence of Alzheimer's Disease and its associated increase in AD risk is stronger amongst black women. #medicine #healthcare #disparity #pollution #environment #neurology #dementia
https://academic.oup.com/biomedgerontology/advance-article-abstract/doi/10.1093/gerona/glab231/6348898?redirectedFrom=fulltext

Differential diagnosis for toxic/metabolic encephalopathies #neurology #medicine #neuroimaging #mri

In a week I'm starting my surgical internship. Waking up again as early as 5:30 a.m., in order to catch the train to Rome and reach the general hospital.
I'm positively excited about this.
#medicine #internship #surgery

A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine. The target, known as ZMYND8, isn't a mutated gene, rather an epigenetic regulatory protein that cancer cells need to control gene expression crucial for them to stay alive and grow.
#medicine #hematology #leukemia #pharmaceuticals
https://www.cell.com/molecular-cell/pdf/S1097-2765(21)00587-6.pdf

Few days ago I came across a patient (A., female, aged 73) who had developed parkinsonism symptoms following a striatocapsular stroke.

I was asked to administer her a screening MMSE. When asked to write down a sentence of her choice –which should include at least a subject and a verb– A. wrote: 'I am tired'.
When I took the paper and realized what she had written, I suddenly felt incredibly small and powerless. #medicine #neurology #parkison #disease

Potential Key mechanism behind synapse degeneration in Alzheimer’s brain discovered

The findings suggest an alternative approach to addressing neurodegenerative disorders: protect glutamatergic synapses by preventing the toxic action of amyloid beta on Wnt/PCP signaling

#neurology #neurobiology #medicine #dementia #alzheimer #disease #pharmacology
https://advances.sciencemag.org/content/7/34/eabh2307

Also, I find that studying on legacy hardware with limited specs holds me back from getting distracted and wasting time. Below a screen dump and a pic of my IBM Thinkpad running NetBSD/i386.
Using Zathura as .pdf reader while streaming Echoes of Bluemars with mplayer.

#retrocomputing #thinkpad #32bit #netbsd
#screenshot #minimalism #medicine #focus

#Introduction ― I'm a 6th year #medicine student, aspiring #neurology
resident. Some topics I'm interested into:

#neuroscience #cognitivescience #neuroimaging #pathology #virology
#bioinformatics #socialism #pacifism #minimalism #collectivism
#cooperatives #environmentalism #climatechange #sustainability
#permaculture #vegan #existentialism #posthumanism #postmodernism #scifi
#cyberpunk #foss #unix #netbsd #sdf #gopher #privacy #bbs
#decentralization #selfhosting #lisp #retrocomputing